ChemSim - your resource for process simulation

  • Are you looking to increase productivity or reduce costs?
  • Do you need help selecting the best simulation software for you?
  • Are you having scheduling issues and bottlenecks?
  • Do you need help developing custom models?

ChemSim's chemical and biochemical engineers are experts in applying process simulation tools to the design and optimization of industrial chemical processes. ChemSim works directly with client engineers to solve important business and engineering problems. Our goal is to maximize the return on your modeling investment.

We can work with your simulation group or we can be your simulation group.

Most recent client presentation: 

"Scheduling Models for Debottlenecking and Throughput Analysis for Large Scale Cell Culture Production" - IBC Conference, Boston, Sept 2005 
Alex Fotopoulos - Biogen, Vince Narbut - Biogen, Ian Gosling - ChemSim 

Services Provided

  • Consulting, on all aspects of process simulation
  • Expertise in many flowsheet simulators including Aspen Plus, Batch Plus, Hysys, Pro/II,SuperPro and SchedulePro
  • Customized Training Courses  
  • Software Integration solutions


  • Steady State and Dynamic Simulation
  • Batch Processes
  • Advanced Physical Properties
  • Bioprocess Simulation
  • Pinch Technology
  • Economic Analysis

We have many years of  experience applying the suite of tools developed by Aspen Technology so if you need a little help regressing physical properties, converging a large flowsheet, or implementing a 'user' model we can help. 

Today, more groups are looking at dynamic modeling using Aspen Dynamics and Aspen Custom Modeler (ACM). However with these products it is important to structure the problem in a manner which facilitates solution of the equations. We have the experience to smooth the migration from the steady state, Aspen Plus solution, to the most appropriate dynamic solution. 

For dynamic modeling, an alternative approach to ACM and Aspen Dynamics is the
modeling solution of gPROMS
, from PSE Ltd. 

Our team also has experience with product suites from Hyprotech -  now part of Aspen Technology, as well as the product offerings from Intelligen, PD-PLUS and others. We can also provide custom solutions based on Excel with a Visual Basic interface.

If you need little more than a spreadsheet for calculations, or you need an equivalent to Visio to quickly layout a process flow diagram, or have a batch process why not try SuperPro Designer from Intelligen!  For process scheduling problems where Project is not suitable, try SchedulePro. 

There are many simulation tools available, ranging in complexity and price! We use the most suitable tool to solve the clients problem. 

Biopharmaceutical Process Simulation and Scheduling

The optimal operation of Biopharmaceutical processes poses a unique set of problems for the process engineer. Although the process is operating in a validated environment there is still the need to improve productivity and reduce costs. 

For batch operations in multiproduct facilities use the combination of SuperPro and
to investigate scheduling, resource requirements, bottlenecks, etc. See a simplified example of modeling a multiproduct biopharmaceutical facility.

For a more in depth discussion of Bioprocess Simulation Strategies in pdf format. "Optimizing productivity in multiproduct batch facilities"
(Genetic Engineering News - Sept 2003.) 

And for an updated summary on the latest tools and techniques used for bioprocess simulation see our article;  " Process Simulation and Modeling for Industrial Biotechnology: Tools and Techniques". 
(Industrial Biotechnology - Vol1, No.2, Summer 2005) 

For more information, see a brochure of our capabilities. 



Voice 781.643.1908    Fax 781.648.1234 


General e-mail: info@ChemSim.com

Web site e-mail: webmaster@ChemSim.com
2002-2004, ChemSim - Last updated 10/12/05